mouse monoclonal IgG1; ZIP10 Antibody (1F6) is an IgG1 κ mouse monoclonal ZIP10 antibody (also designated ZIP10 antibody) that detects the ZIP10 protein of human origin by WB, IP and ELISA. ZIP10 Antibody (1F6) is available as the non-conjugated anti-ZIP10 antibody. ZIP10 (Zinc transporter ZIP10, Solute carrier family 39 member 10) is a multi-pass (seven transmembrane regions) membrane protein that belongs to the ZIP transporter (TC 2.A.5) family. Zinc transporters all have transmembrane domains, and are encoded by two SLC (solute-linked carrier) gene families: ZnT (SLC30) and Zip (SLC39). There are at least 9 ZnT and 15 Zip transporters in human cells. Zip transporters are believed to increase intracellular zinc by promoting zinc uptake. This may be facilitated by vesicles within the cell that release release into the cytoplasm. Zip and ZnT transporter families exhibit tissue-specific expression and respond differently to zinc deficiency and excess. High expression levels of ZIP10 can be correlated with invasiveness of several metastatic breast cancers.