mouse monoclonal IgM; PIP2 Antibody (PIP2 2C11) is an IgM κ mouse monoclonal PIP2 antibody (also designated Liposome marker antibody, Liposomal marker antibody, Phosphatidylinositol 4,5-bisphosphate antibody, dipalmitoyl PtdIns(4,5)P2 antibody, PtdIns(3,4,5)P3 antibody, Liposomes (PBS / lipid A / phosphatidylcholine (PC) / cholesterol / synthetic di-palmitoyl PtdIns(4,5)P2) antibody, 1,2-Diacyl-sn-glycero-3-phospho-(1-D-myo-inositol 4,5-bisphosphate) antibody, Phosphatidylinositol 4,5-bisphosphate antibody, Phosphatidylinositol biphosphate antibody, Phosphatidylinositol diphosphate antibody, PIP 2 antibody, or PtdIns(4,5)P2 antibody) that detects the PIP2 protein of mouse, rat and human origin by IP and IF. PIP2 Antibody (PIP2 2C11) is available as the non-conjugated anti-PIP2 antibody. Phosphatidylinositol 4,5-biphosphate (PIP2) is a low-abundance membrane phospholipid that functions in a variety of cellular processes, such as membrane trafficking, plasma membrane-cytoskeleton linkages, synaptic vesicle recycling, second messenger signaling, cell adhesion and motility and regulation of proteins involved in phospholipid metabolism. It also stimulates the Ca2+-activated ATPase, implicating that changes in the cellular concentration of PIP2 may be important in regulating Ca2+ transport by the endoplasmic reticulum. PIP2 and intracellular Ca2+ regulate the taste transduction ion channel TRPM5. PIP2 serves as an effector of multiple downstream proteins and its levels are regulated by hormones. It may also serve as a second messenger in the control of cytoskeleton-membrane adhesion.