mouse monoclonal IgG2b; PP2A-Cα/β Antibody (1D6) is an IgG2b κ mouse monoclonal PP2A-Cα/β antibody (also designated PP2A-Cα/β antibody or PP2A phosphatase catalytic subunit C alpha/beta antibody) that detects PP2A-Cα/β of mouse, rat and human origin by WB, IP, IF and IHC(P). PP2A-Cα/β Antibody (1D6) is available as the non-conjugated anti-PP2A-Cα/β antibody form, as well as multiple conjugated forms of anti-PP2A-Cα/β antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2Aα and PP2Aβ. The PP2A catalytic subunit associates with a variety of regulatory subunits. Regulatory subunits include PP2A-Aα and -Aβ, PP2A-Bα and -Bβ, PP2A-Cα and -Cβ, and PP2A-B56α and -B56β.