An RNA virus is a type of virus that has RNA as genetic material. As the RNA virus enters the host, the virus makes use of the presence of endogenous cellular RNA-dependent RNA polymerases. This allows the virus to replicate its genome and integrate itself into the host's DNA. Once integrated, the virus may become latent (such as in HIV infection) or maybe be transcribed to continually produce new viral proteins (such as in SARS-CoV-2 infection). Examples of RNA viruses include the hepatitis C virus, the virus that causes Ebola, SARS-CoV-2 (the virus that causes the COVID-19 disease), polio, measles, and the HIV virus.
The downstream processing of virus particles, vesicles, RNAs, plasmids and other forms of DNA, contains multiple interdependent steps, each requiring optimization for best results. This webi...
The use of adeno-associated viruses (AAV) as gene delivery vectors has vast potential for the treatment of many severe human diseases. A small group of intensively studied AAV capsids have b...
Vaccines against SARS-CoV-2 have been made in a record time. However, although the vaccines that have been deployed have clearly reduced the percentage of severe infections in countries wher...
First Broadcast: Date: October 12, 2022 Time: 8:00am PDT, 11:00am EDT Second Broadcast: Date: October 12, 2022 Time: 9:00am SGT The new Embedded CryoSPARC Live, now fully integrated with t...
Date: August 10, 2022 Time: 10:00am PDT, 1:00pm EDT The global pandemic has increased focus and scrutiny on molecular diagnostic assay development, resulting in a need for assays that provid...
Date: July 28, 2022 Time: 6:00am (PDT), 9:00am (EDT) Hepatitis B and C continues to be a leading cause of global morbidity and mortality, resulting in 1.1 million deaths and 3 million new in...
Date: December 14, 2021 Time: 6:00am (PST), 9:00am (EST) Hepatitis E virus (HEV) is a single-stranded positive-sense RNA virus and is a leading cause of acute viral hepatitis worldwide. The...
Date: November 15, 2021 Time: 6:00am (PDT), 9:00am (EDT) Targeted sequencing of respiratory viruses’ genomes is important to identify novel viral variants. Compared to amplicon sequenc...
Date: October 28, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Loop-mediated isothermal amplification (LAMP) uses a stand-displacing DNA polymerase and four to six primers to rapidly amplify DNA a...
Vaccination and infection are two different paths to immunity. Understanding human immune responses to SARS-CoV-2 RNA vaccines is of interest for a panoply of reasons. mRNA vaccines have dem...
SARS-CoV-2 is an emergent virus. Specifically how it will adapt to human hosts and populations with growing immunity is unknown. Coronaviruses acquire substitutions more slowly than other RN...
Date: October 7, 2021 Time: 8:00am (PDT), 11:00am (EDT) To combat the COVID-19 pandemic, comprehensive characterization of humoral and cellular immune responses to SARS-CoV-2 is essential. A...
Date: September 27, 2021 Time: 3:00am (PDT), 6:00am (EDT), 12pm (CET) Experts are predicting an increase in influenza cases and a constant presence of SARS-CoV-2 in the shortly approaching i...
Date: September 16, 2021 Time: 9:00am (PDT), 12:00pm (EDT) For diagnostic testing, proper sample collection and transport play a pivotal role in the accurate and timely identification of a p...
The ongoing COVID-19 pandemic has elevated the need for reliable, cost-effective means for widespread virus detection. This webinar will explore two distinct approaches for isolating viral R...
Early detection is critical for prompt and effective treatment of acute infectious diseases. For tick-borne diseases (TBD), the lack of accurate early diagnosis can result in delayed treatme...
Analysis of community wastewater has been shown to be an effective method for tracking the prevalence of SARS-COV-2. Our group has developed techniques for sequencing a portion of the SARS-C...
Ribonucleic acid (RNA) has a breathtaking variety of biological functions, which far exceeds its classical role as a carrier of genetic information. The repertoire of this versatile molecule...
We currently do not have effective vaccines or antiviral drugs for most of the viral diseases that afflict humans. Antiviral therapies that enable long-term control over human immunodeficien...
Varicella zoster virus (VZV) causes two clinically distinct forms of disease, varicella and herpes zoster. These forms can each present with multiple manifestations ranging from lesions incl...
Highly efficacious vaccines against COVD-19 have been generated in a record time, and allowed a great impact in preventing severe disease due to SARS-CoV-2 infection in vaccinated individual...
Self-amplifying RNA replicons are promising candidates for next generation vaccines against human coronaviruses with pandemic potential. Self-amplification of RNAs in host cells generates mo...
Influenza viruses represent a significant burden to human health. In order to limit respiratory viral disease, new approaches that can prevent viral infection and spread are needed. We have...
Innate and adaptive immunity mechanisms provide antiviral protection in mammals. In this talk, I shall present recent findings from my lab and collaborators revealing a distinct form of mamm...
The downstream processing of virus particles, vesicles, RNAs, plasmids and other forms of DNA, contains multiple interdependent steps, each requiring optimization for best results. This webi...
The use of adeno-associated viruses (AAV) as gene delivery vectors has vast potential for the treatment of many severe human diseases. A small group of intensively studied AAV capsids have b...
Vaccines against SARS-CoV-2 have been made in a record time. However, although the vaccines that have been deployed have clearly reduced the percentage of severe infections in countries wher...
First Broadcast: Date: October 12, 2022 Time: 8:00am PDT, 11:00am EDT Second Broadcast: Date: October 12, 2022 Time: 9:00am SGT The new Embedded CryoSPARC Live, now fully integrated with t...
Date: August 10, 2022 Time: 10:00am PDT, 1:00pm EDT The global pandemic has increased focus and scrutiny on molecular diagnostic assay development, resulting in a need for assays that provid...
Date: July 28, 2022 Time: 6:00am (PDT), 9:00am (EDT) Hepatitis B and C continues to be a leading cause of global morbidity and mortality, resulting in 1.1 million deaths and 3 million new in...
Date: December 14, 2021 Time: 6:00am (PST), 9:00am (EST) Hepatitis E virus (HEV) is a single-stranded positive-sense RNA virus and is a leading cause of acute viral hepatitis worldwide. The...
Date: November 15, 2021 Time: 6:00am (PDT), 9:00am (EDT) Targeted sequencing of respiratory viruses’ genomes is important to identify novel viral variants. Compared to amplicon sequenc...
Date: October 28, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Loop-mediated isothermal amplification (LAMP) uses a stand-displacing DNA polymerase and four to six primers to rapidly amplify DNA a...
Vaccination and infection are two different paths to immunity. Understanding human immune responses to SARS-CoV-2 RNA vaccines is of interest for a panoply of reasons. mRNA vaccines have dem...
SARS-CoV-2 is an emergent virus. Specifically how it will adapt to human hosts and populations with growing immunity is unknown. Coronaviruses acquire substitutions more slowly than other RN...
Date: October 7, 2021 Time: 8:00am (PDT), 11:00am (EDT) To combat the COVID-19 pandemic, comprehensive characterization of humoral and cellular immune responses to SARS-CoV-2 is essential. A...
Date: September 27, 2021 Time: 3:00am (PDT), 6:00am (EDT), 12pm (CET) Experts are predicting an increase in influenza cases and a constant presence of SARS-CoV-2 in the shortly approaching i...
Date: September 16, 2021 Time: 9:00am (PDT), 12:00pm (EDT) For diagnostic testing, proper sample collection and transport play a pivotal role in the accurate and timely identification of a p...
The ongoing COVID-19 pandemic has elevated the need for reliable, cost-effective means for widespread virus detection. This webinar will explore two distinct approaches for isolating viral R...
Early detection is critical for prompt and effective treatment of acute infectious diseases. For tick-borne diseases (TBD), the lack of accurate early diagnosis can result in delayed treatme...
Analysis of community wastewater has been shown to be an effective method for tracking the prevalence of SARS-COV-2. Our group has developed techniques for sequencing a portion of the SARS-C...
Ribonucleic acid (RNA) has a breathtaking variety of biological functions, which far exceeds its classical role as a carrier of genetic information. The repertoire of this versatile molecule...
We currently do not have effective vaccines or antiviral drugs for most of the viral diseases that afflict humans. Antiviral therapies that enable long-term control over human immunodeficien...
Varicella zoster virus (VZV) causes two clinically distinct forms of disease, varicella and herpes zoster. These forms can each present with multiple manifestations ranging from lesions incl...
Highly efficacious vaccines against COVD-19 have been generated in a record time, and allowed a great impact in preventing severe disease due to SARS-CoV-2 infection in vaccinated individual...
Self-amplifying RNA replicons are promising candidates for next generation vaccines against human coronaviruses with pandemic potential. Self-amplification of RNAs in host cells generates mo...
Influenza viruses represent a significant burden to human health. In order to limit respiratory viral disease, new approaches that can prevent viral infection and spread are needed. We have...
Innate and adaptive immunity mechanisms provide antiviral protection in mammals. In this talk, I shall present recent findings from my lab and collaborators revealing a distinct form of mamm...
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