Research models are used in medical research to mimic aspects of a disease or illness that occurs in humans. Research models can include animals (in vivo models), cell lines (in vitro models), or computer-driven demonstrations (in silico models). Research models allow doctors and scientists to uncover important information that can be applied to clinical practice.
Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
The cytolytic activity of Immune cells toward cancer cells is finely regulated through several pathways and receptors. Although end point assays have been routinely used to measure cell kill...
With the recent successes of immunotherapies, a fresh breeze of optimism in the fight against cancer has reinvigorated the industry. Perhaps the greatest legacy will be the realization of th...
B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
Background: Acute liver injury (ALI) is characterised by hepatocyte death and liver inflammation. Macrophages play a pivotal role in ALI by phagocytosing dead cells and producing pro-regener...
Three dimensional (3D) spheroidal cell models have become a mainstay in life science research to provide the most in vivo-like environment. Performing media exchanges and washes with unattac...
Metastasis is the main cause of death in cancer patients and one of the most complex biological processes in human diseases (Hanahan et al., 2011). The development of therapies designed to f...
The use of three‐dimensional (3D) culture models is rapidly expanding due to their recognition as representing more structurally and physiologically relevant models of in vivo biology. 3D ce...
DATE: July 9, 2020 TIME: 11:00am PT Maladaptive aggression is an immutable force that contributes to the suffering and death of millions of people around the world annually, as well as prese...
Brain malignancies can either originate from within the CNS (gliomas) or invade from other locations in the body (metastases). A highly immunosuppressive tumor microenvironment (TME) influen...
High production ability has been used for primary selection in dairy breeding schemes. In particular, milk yield, fat yield, and protein yield are the most important economic traits for dair...
DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
DATE: June 30, 2020 TIME: 8:00am PT, 11:00am Understanding the tumor microenvironment (TME) is essential for the development of effective treatments for cancer patients. Traditional multi...
DATE: June 24, 2020 TIME: 9:00am PT, 12:00pm ET Some of the key factors in viral pathogenesis are the molecular mechanisms enabling viral entry into cells. Inhibitors of viral entry are ofte...
DATE: June 18, 2020 TIME: 9:00am PDT, 12:00pm EDT Despite the success of immunotherapy against several malignancies including melanoma and lung adenocarcinoma, glioblastoma remains the excep...
Are you interested in Novel Sample Prep and gaining Powerful Insights with Discovery-based LC/MS Workflows? In this session, we will demonstrate a complete untargeted metabolomics workflow f...
Bringing a new research surgical model into production is always a challenging endeavor, and it has become much more challenging with the emergence of the Covid-19 pandemic. The virus’...
Understanding the complex interplay between a pathogen and the host response is important to developing effective vaccines and therapeutics. The nCounter® Analysis System and GeoMx®...
Since the outbreak of the Covid-19 pandemic, the development of diagnostics for both the virus (molecular) and the host immune response (serological) has become essential for monitoring the...
DATE: June 16, 2020 TIME: 8:00am PT Multi-wavelength analysis of hydrodynamic data collected on the latest analytical ultracentrifugation instruments provides additional resolution and insig...
DATE: June 9, 2020 TIME: 6am PT, 9am ET, 3pm CEST The importance of disposable plastic consumables and their overall impact on the experimental workflow of qPCR has been taken into considera...
Understanding morphogenesis is an inherently four-dimensional problem, as cells change position in space and the embryo is transformed over time. Dorsal intercalation of epidermal cells in t...
Cancer initiation and virulence depends on mechanisms to evade host immunosurveillance and suppression of early invasion and growth. Distinct phenotypes of the immune infiltrates in and arou...
Immune checkpoint therapies targeting the CTLA-4 and PD-(L)1 pathways have been largely clinically disappointing for patients with prostate cancer. This can be attributed to the highly immun...
Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
The cytolytic activity of Immune cells toward cancer cells is finely regulated through several pathways and receptors. Although end point assays have been routinely used to measure cell kill...
With the recent successes of immunotherapies, a fresh breeze of optimism in the fight against cancer has reinvigorated the industry. Perhaps the greatest legacy will be the realization of th...
B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H...
Background: Acute liver injury (ALI) is characterised by hepatocyte death and liver inflammation. Macrophages play a pivotal role in ALI by phagocytosing dead cells and producing pro-regener...
Three dimensional (3D) spheroidal cell models have become a mainstay in life science research to provide the most in vivo-like environment. Performing media exchanges and washes with unattac...
Metastasis is the main cause of death in cancer patients and one of the most complex biological processes in human diseases (Hanahan et al., 2011). The development of therapies designed to f...
The use of three‐dimensional (3D) culture models is rapidly expanding due to their recognition as representing more structurally and physiologically relevant models of in vivo biology. 3D ce...
DATE: July 9, 2020 TIME: 11:00am PT Maladaptive aggression is an immutable force that contributes to the suffering and death of millions of people around the world annually, as well as prese...
Brain malignancies can either originate from within the CNS (gliomas) or invade from other locations in the body (metastases). A highly immunosuppressive tumor microenvironment (TME) influen...
High production ability has been used for primary selection in dairy breeding schemes. In particular, milk yield, fat yield, and protein yield are the most important economic traits for dair...
DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
DATE: June 30, 2020 TIME: 8:00am PT, 11:00am Understanding the tumor microenvironment (TME) is essential for the development of effective treatments for cancer patients. Traditional multi...
DATE: June 24, 2020 TIME: 9:00am PT, 12:00pm ET Some of the key factors in viral pathogenesis are the molecular mechanisms enabling viral entry into cells. Inhibitors of viral entry are ofte...
DATE: June 18, 2020 TIME: 9:00am PDT, 12:00pm EDT Despite the success of immunotherapy against several malignancies including melanoma and lung adenocarcinoma, glioblastoma remains the excep...
Are you interested in Novel Sample Prep and gaining Powerful Insights with Discovery-based LC/MS Workflows? In this session, we will demonstrate a complete untargeted metabolomics workflow f...
Bringing a new research surgical model into production is always a challenging endeavor, and it has become much more challenging with the emergence of the Covid-19 pandemic. The virus’...
Understanding the complex interplay between a pathogen and the host response is important to developing effective vaccines and therapeutics. The nCounter® Analysis System and GeoMx®...
Since the outbreak of the Covid-19 pandemic, the development of diagnostics for both the virus (molecular) and the host immune response (serological) has become essential for monitoring the...
DATE: June 16, 2020 TIME: 8:00am PT Multi-wavelength analysis of hydrodynamic data collected on the latest analytical ultracentrifugation instruments provides additional resolution and insig...
DATE: June 9, 2020 TIME: 6am PT, 9am ET, 3pm CEST The importance of disposable plastic consumables and their overall impact on the experimental workflow of qPCR has been taken into considera...
Understanding morphogenesis is an inherently four-dimensional problem, as cells change position in space and the embryo is transformed over time. Dorsal intercalation of epidermal cells in t...
Cancer initiation and virulence depends on mechanisms to evade host immunosurveillance and suppression of early invasion and growth. Distinct phenotypes of the immune infiltrates in and arou...
Immune checkpoint therapies targeting the CTLA-4 and PD-(L)1 pathways have been largely clinically disappointing for patients with prostate cancer. This can be attributed to the highly immun...
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