Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
Years of significant effort can go into generating key proof of concept data to support moving bench research to clinical development.Yet, much work remains in order to transition from POC to...
The study of human genetic neurodevelopmental disorders (NDDs) is complicated by the inaccessibility of the relevant tissue for study: it is extremely rare to obtain post-surgical brain sampl...
The human umbilical cord is a promising abundant source of mesenchymal stem cells (MSCs). Compare to other MSCs, the advantages of human umbilical cord MSCs (hUC-MSCs) are easily accessible a...
One of the ultimate goals in Regenerative Medicine is the generation of pluripotent stem cells (PSCs) directly from somatic cells obtained from patients. Although major findings in the defini...
Neuropathic pain and bladder dysfunction represent significant quality of life issues for many spinal cord injury patients. Loss of GABAergic tone in the injured spinal cord may contribute to...
Using human pluripotent stem cells as a screening platform, we have identified a novel cell surface maker that identifies foregut endoderm progenitors in pancreas and liver. We have sho...
Buerger’s disease, commonly known as Thromboangiitis obliterans, is a non-atherosclerotic, segmental inflammatory disease that can affect the small and medium-sized arteries of young pe...
A major challenge for the clinical application of pluripotent stem cell therapy for neurodegenerative diseases is large-scale manufacturing and cryopreservation of neurons and glia that can b...
Mesenchymal stromal cell (MSC) therapy is a promising option to support endogenous regeneration and immunomodulation. However, the clinical results are contradictory. We think that the recent...
The human body is composed of about 200 different cell types. The identity and function of these distinct cell types are precisely programmed by the regulatory networks encoded in the 3 billi...
The human enteric nervous system (ENS) is derived from the neural crest and represents a complex network of ~500 million neurons with dozens of distinct neurotransmitter and hormone subtypes ...
Stem cells, specifically induced pluripotent stem cells (iPSCs), offer exciting potential for the future of cell therapy and regenerative medicine. More recently, genetic engineering of stem ...
Neurons derived from human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), are excellent resources for disease modeling and d...
Access this training to learn more about the evolution of pluripotent stem cell culture systems and which solution is best for your PSC culture goals....
Access this training to learn more about different techniques that can be used for successful colony selection and passage of induced pluripotent stem cells....
The reprogramming of somatic cells into induced Pluripotent Stem Cells (iPSC) has great potential of applications, not only in basic research, but also in drug screening and cell therapy. Wit...
DATE: August 24th 2016TIME: 8:00AM PST, 11:00AM ESTPreclinical micro-computed tomography (microCT) imaging systems are utilized across a wide range of applications requiring imagi...
DATE: June 30, 2016
TIME: 8:00am Pacific time, 11:00am Eastern time
Focusing solely on malignant cancer cells and the genes that they express is modestly just a glimpse of the...
Precision medicine requires success in two intertwined aspects: precision therapy and personalized medicine. Precision therapy is being able to effectively treat the right disease; to have th...
Antibodies are tremendously useful and versatile tools and they have found use in many areas of life science research. However, antibodies can be difficult to make and are used in inherently...
High content imaging and analysis offers a robust, high throughput method for analyzing large numbers of cells with the benefit of the spatial and temporal demarcation afforded by fluorescenc...
In this presentation, we will go over some of the reasons you would want to consider using fluorescence imaging and give a brief introduction to using fluorescent probes for cell structure an...
DATE: June 23, 2016
TIME: 11:00am Pacific time, 2:00pm Eastern time
T cells as part of the adaptive immune system play a central role in cell-mediated immunity. Their link to ...
DATE: June 15, 2016TIME: 08:00AM PDT, 11:00AM EDT, 3:00PM GMT Positron Emission Tomography (PET) is a 3-dimensional, quantitative imaging technology that has robust clinical trans...
Years of significant effort can go into generating key proof of concept data to support moving bench research to clinical development.Yet, much work remains in order to transition from POC to...
The study of human genetic neurodevelopmental disorders (NDDs) is complicated by the inaccessibility of the relevant tissue for study: it is extremely rare to obtain post-surgical brain sampl...
The human umbilical cord is a promising abundant source of mesenchymal stem cells (MSCs). Compare to other MSCs, the advantages of human umbilical cord MSCs (hUC-MSCs) are easily accessible a...
One of the ultimate goals in Regenerative Medicine is the generation of pluripotent stem cells (PSCs) directly from somatic cells obtained from patients. Although major findings in the defini...
Neuropathic pain and bladder dysfunction represent significant quality of life issues for many spinal cord injury patients. Loss of GABAergic tone in the injured spinal cord may contribute to...
Using human pluripotent stem cells as a screening platform, we have identified a novel cell surface maker that identifies foregut endoderm progenitors in pancreas and liver. We have sho...
Buerger’s disease, commonly known as Thromboangiitis obliterans, is a non-atherosclerotic, segmental inflammatory disease that can affect the small and medium-sized arteries of young pe...
A major challenge for the clinical application of pluripotent stem cell therapy for neurodegenerative diseases is large-scale manufacturing and cryopreservation of neurons and glia that can b...
Mesenchymal stromal cell (MSC) therapy is a promising option to support endogenous regeneration and immunomodulation. However, the clinical results are contradictory. We think that the recent...
The human body is composed of about 200 different cell types. The identity and function of these distinct cell types are precisely programmed by the regulatory networks encoded in the 3 billi...
The human enteric nervous system (ENS) is derived from the neural crest and represents a complex network of ~500 million neurons with dozens of distinct neurotransmitter and hormone subtypes ...
Stem cells, specifically induced pluripotent stem cells (iPSCs), offer exciting potential for the future of cell therapy and regenerative medicine. More recently, genetic engineering of stem ...
Neurons derived from human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), are excellent resources for disease modeling and d...
Access this training to learn more about the evolution of pluripotent stem cell culture systems and which solution is best for your PSC culture goals....
Access this training to learn more about different techniques that can be used for successful colony selection and passage of induced pluripotent stem cells....
The reprogramming of somatic cells into induced Pluripotent Stem Cells (iPSC) has great potential of applications, not only in basic research, but also in drug screening and cell therapy. Wit...
DATE: August 24th 2016TIME: 8:00AM PST, 11:00AM ESTPreclinical micro-computed tomography (microCT) imaging systems are utilized across a wide range of applications requiring imagi...
DATE: June 30, 2016
TIME: 8:00am Pacific time, 11:00am Eastern time
Focusing solely on malignant cancer cells and the genes that they express is modestly just a glimpse of the...
Precision medicine requires success in two intertwined aspects: precision therapy and personalized medicine. Precision therapy is being able to effectively treat the right disease; to have th...
Antibodies are tremendously useful and versatile tools and they have found use in many areas of life science research. However, antibodies can be difficult to make and are used in inherently...
High content imaging and analysis offers a robust, high throughput method for analyzing large numbers of cells with the benefit of the spatial and temporal demarcation afforded by fluorescenc...
In this presentation, we will go over some of the reasons you would want to consider using fluorescence imaging and give a brief introduction to using fluorescent probes for cell structure an...
DATE: June 23, 2016
TIME: 11:00am Pacific time, 2:00pm Eastern time
T cells as part of the adaptive immune system play a central role in cell-mediated immunity. Their link to ...
DATE: June 15, 2016TIME: 08:00AM PDT, 11:00AM EDT, 3:00PM GMT Positron Emission Tomography (PET) is a 3-dimensional, quantitative imaging technology that has robust clinical trans...
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