Infectious Disease: Infectious diseases are caused by pathogenic microorganisms, such as bacteria, viruses, parasites or fungi; the diseases can be spread, directly or indirectly, from one person to another. Zoonotic diseases are infectious diseases of animals that can cause disease when transmitted to humans. Most infectious diseases have only minor complications. But some infections - such as pneumonia, AIDS and meningitis - can become life-threatening.
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  Influenza is a major clinical and public health issue. Rapid, accurate diagnostics for influenza have the potential to improve the efficacy of therapy, limit antibiotic over-use, conserve ...
Protein-protein interactions and allosterically regulated enzymes have been challenging but important targets for probe- and drug discovery. We and others have found that fragment-based lead...
In the past decade, we have witnessed an explosion in the availability of high-resolution structural information that sheds light on the binding of diverse classes of ligands to both soluble...
Antibiotics are among the most important advances in the history of modern medicine. They turned often acutely fatal infections into treatable indications with radical cures. Antibiotics co...
Accurate and timely diagnosis of rejection and infection is essential for long-term survival of solid-organ transplant recipients. We evaluated the performance a novel test to monitor rejecti...
Next-Generation Sequencing is enabling scientists to study the transcriptome in ways never before possible. During this session with Illumina Distinguished Scientist, Dr. Gary Schroth, you w...
In 2010, our team of synthetic biologists announced the creation of a bacterial cell that had a chemically synthesized genome. To build this synthetic Mycoplasma mycoides JCVI 1.0 we had to d...
Serology testing continues to be an indispensable tool for the management of several disease states, especially treponemal screening to monitor syphilis infection in the US. Come to this edu...
Vaginitis and vaginosis, including Bacterial Vaginosis (BV), Vulvovaginal Candidiasis (VVC), and Trichomoniasis (TV), are extremely common conditions, consuming many healthcare resources and...
What is the future of personalized medicine? Featuring Dr. Trevor Hawkins (An Introduction to Companion Diagnostics), Dr. Patrick Joseph (Making It Personal for Patients), and Dr. Richard Fra...
Human papillomavirus (HPV) is the primary cause of cervical cancer and more than 100 types of HPV have been identified. Detection of HPV from cervical samples is associated with a 250 times...