Chimeric antigen receptors (CAR) T cells are a specialized therapy used as a cancer treatment in which a patient's immune cells are engineered to better identify and kill cancer cells. CAR T cell therapy can be effective for some types of leukemias and lymphomas but they also have the capacity to damage healthy calls, including B cells, the immune cells responsible for secreting antibodies. Many vaccines work by inducing your body to produce antibodies in response to a specific stimulus against which the vaccine is targeted. Therefore, studying how to maintain vaccine efficacy following CAR T cell therapy is an important research focus.
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Flow cytometry plays a crucial role in the rapidly growing field of cell therapy, this method is used to identify different types of cells throughout the manufacturing process, from initial...
The therapeutic use of chimeric antigen receptor T cells has achieved significant success in the treatment of B cells malignancies. Despite promising results in mouse tumor models, a similar...
Date: November 09, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) The field of cell and gene therapy is rapidly growing. In particular, the use of lentiviruses in CAR-T applications is...
COVID-19 remains a global health emergency with limited treatment options, lagging vaccine rates, and inadequate healthcare resources in the face of an ongoing calamity. The disease is chara...
Date: October 12, 2022, October 13, 2022 Time: 8:30pm (PDT), 11:30pm (EDT), 5:30am (CEST) High dimensional full spectrum flow cytometry holds the promise of addressing long-held questions in...
The COVID-19 pandemic has taken a dramatic toll worldwide. Its impact possibly has been the most palpable amongst uniquely vulnerable groups of patients, such as patients with a cancer diagn...
Date: December 08, 2021 Time: 8:00am (PDT), 11:00am (EDT) Learn how enrichment of primary dendritic cell (DC) subsets and sustainable DC manufacturing advances DC-based cell therapies. In th...
Date: November 18, 2021 Time: 8:00am (PDT), 11:00am (EDT) Keep ahead in CAR T and CAR NK cell research. We introduce advanced techniques for generating and characterizing engineered immune c...
Date: November 3, 2021 Time: 7:00am (PDT), 10:00am (EDT) The reconstitution of a fully functional human immune system in mouse after engraftment of purified hCD34+ hematopoietic cells provid...
Summary: Cancer neoantigens are highly specific to the tumor, potently immunogenic and can be targeted by both vaccines and engineered cellular therapies. This talk will introduce the defini...
Date: July 27, 2021 Time: 8:00am (PDT), 11:00am (EDT) The Origin of Biopharmaceutics (Biopharma) derive from The Division of Clinical Research in the U.S. Bureau of Medicine. However, author...
Gene editing technologies such as CRISPR/Cas9 have greater flexibility and high efficiency. CRISPR technology enables targeted insertion of transgenes at the desired locus and has the abilit...
Date: February 10, 2021 Time: 8:00am (PST), 11:00am (EST) Uncovering the interactions between the immune system and cancer cells or pathogens is key for understanding and controlling both ca...
DATE: November 4th, 2020 TIME: 11:00am PST As cell therapies become more complex, the need for robust analytical tools to characterize such products as they enter the clinic has increased in...
B cells and tertiary lymphoid structures (TLS) promote immunotherapy response 1:00–1:30 pm PDT Presented By: Rafet Basar, MD...