MAR 27, 2025 10:55 AM PDT

Fighting Plaque with CBD: Study Shows Enhanced Oral Health Benefits

Can cannabidiol (CBD) serve as a mouthwash to combat gingivitis? This is what a recent study published in the Journal of Clinical Medicine hopes to address as a team of researchers from the Medical University of Silesia in Poland investigated how mouthwash containing CBD oil could be used as an effective agent for combating gingivitis. This study has the potential to help researchers, medical professionals, and the public better understand the benefits of CBD in oral hygiene, specifically towards fighting diseases.

For the study, the researchers evaluated 40 participants, some using a CBD-infused mouthwash twice a day for 30 seconds each and some part of a control group, over 42 days to ascertain their oral microbiome, bleeding on probing (BOP), and approximate plaque index (API) pre- and post-treatment. In the end, the researchers found decreases in API and BOP in all groups, along with significant reductions in baseline BOP-1 scores and improved API scores.

The study concludes, “Firstly, the use of a mouthwash containing cannabidiol (CBD) and spilanthol was demonstrated to be efficacious in the maintenance of oral microbiota homeostasis. Secondly, the combination of TTO with spilanthol and CBD in the rinse was shown to result in a more significant reduction in selected oral health parameters (BOP and API) and anti-inflammatory effects when compared to a rinse with TTO alone. It should be noted that this is a pilot study and will continue.”

This study comes after a 2020 study published in the Journal of Cannabis Research found that CBD-infused mouthwash was effective at treating dental plaque in several dozen patients in Belgium. Therefore, this most recent study builds on a growing body of knowledge regarding the benefits of CBD oil in oral hygiene.

How will CBD-infused mouthwash contribute to oral hygiene in the coming years and decades? Only time will tell, and this is why we science!

As always, keep doing science & keep looking up!

Sources: Journal of Clinical Medicine, Marijuana Moment, Journal of Cannabis Research  

About the Author
Master's (MA/MS/Other)
Laurence Tognetti is a six-year USAF Veteran who earned both a BSc and MSc from the School of Earth and Space Exploration at Arizona State University. Laurence is extremely passionate about outer space and science communication, and is the author of "Outer Solar System Moons: Your Personal 3D Journey".
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