Investigating Polymeric Nanocarriers for Efficient RNA Delivery

Genetic drugs have the potential to revolutionize the way we treat diseases, but a major challenge has been finding effective means of delivering genetic material to cells in the body. Polymeric nanoparticles have emerged as a promising solution to overcome the delivery hurdle, due to their ability to protect and target genetic material to the target site. In this presentation, I will present findings on how changing the surface of polymeric nanoparticles created unique nanocarriers and caused them to interact specifically with the target cells in an animal disease model of inflammation. In addition, I will discuss the journey of polymeric nanoparticles within cancer cells, visualize the process of gene delivery, and present various labeling methods and their impact on cellular behavior and cell-nanomaterial interactions. This talk will provide an overview of the current state of the field and future directions for research in this exciting area.

Learning Objectives: 

1. Discuss the rationale for genetic drugs.

2. Differentiate RNA delivery barriers and the motivation for nanocarriers.

3. Discuss polymeric nanocarriers as next-generation RNA therapeutics.