Assistant Professor
BIOGRAPHY
Speaker
Event Date & Time
Date: April 26, 2022
Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CET)
Abstract
Cell competition is a mechanism of interaction that dictates cell selection based on differences in cellular fitness. We developed a model of mixed murine organoids and enteroid monolayers to study such complex cellular interactions in a mammalian system. We combined this model with (time-lapse) microscopy and transcriptome analysis to show that cell competition drives growth of cancer cells by active out-competition of wild-type cells through forced cell death and cell-state change in a JNK-dependent manner.
Learning Objectives
- Identify generation of mixed murine organoids and enteroid monolayers
- Discuss the use of (time-lapse) microscopy to follow cellular behavior
- Discover insight in the role of cell competition in tumor growth
Webinars will be available for unlimited on-demand viewing after live event.
LabRoots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this webinar, you can earn 1 Continuing Education credit once you have viewed the webinar in its entirety.
You May Also Like
DEC 10, 2024 | 9:00 AM
To-date, proteomic analysis has been severely limited in scale and resolution. Analyzing protein samples using an intact, single-molecule approach holds th...
OCT 02, 2024 | 7:30 AM
De novo gene synthesis and protein expression are established technologies that can give access to nearly any target DNA or protein sequence, allowing for engineering of biologics. In this p...
Loading Comments...