Optimizing Nucleic Acid Extraction: Accelerating Progress and Ensuring Quality in Cell and Gene Therapy Development

The development of cell and gene therapies faces immense pressure in terms of time and cost. Advanced therapy medicinal products (ATMPs) demand stringent quality control measures to ensure safety and efficacy. Nucleic acid extraction is a critical initial step in viral vector quality control and essential for assessing transfection efficiency and for verifying transgene expression or viral DNA integration. In this session, we will explore the advantages and limitations of various nucleic acid extraction techniques, focusing on how to streamline development timelines, reduce costs, and maintain high-quality outcomes.

Learning Objectives:

• Discuss the key challenges in RNA/DNA extraction
• Evaluate different extraction techniques and their impact
• Design strategies to optimize project timelines, reduce costs, and ensure high-quality results