Optimizing retinal cell differentiation of human pluripotent stem cells for large-scale disease modeling.

Human induced pluripotent stem cells (iPSCs) are valuable cells for retinal disease modeling, as these cells are of patient origin and can be differentiated into cell types of interest. This presentation will discuss the differentiation of iPSCs into retinal pigment epithelium cells and retinal ganglion cells and their molecular manipulations for modeling degenerative diseases of the retina and optic nerve.