The Use of Polysaccharide-based Chiral Stationary Phases for the Achiral and Chiral Separation of Cannabinoids; Abridged - Separation of Cannabinoids on Polysaccharide CSPs

Many analyses of cannabis-related products focus on the achiral separation of a mixture of prioritized cannabinoids, and can be done with readily available and established methods and equipment. However, the importance of chiral resolution is growing as new cannabinoids and isomers of THC are chiral (enantiomeric) in nature, and cannot be separated by achiral means. Polysaccharide-based chiral stationary phases (CSPs) have been widely used in the pharmaceutical industry for this purpose for many decades, and are well suited to handle these new challenges for the cannabis industry. This talk will cover the early and current efforts for the separation of cannabinoid mixtures on polysaccharide-based CSPs, both for analytical and preparative applications.

Learning Objectives:

1. Summariz chiral chromatography.

2. Explain alternative cannabis separations.