The advent of next generation sequencing has transformed the way we identify mutations with clinical implications. As the compendium of variants expands, gathering the most current and accurate information is critical to computing variant classifications. Manual curation is laborious, time consuming, and error prone, as information critical to variant interpretation may be missed. The QIAGEN knowledgebase includes the most comprehensive database of variant specific publications, as well as data from third party sources such as ClinVar, HGMD, CentoMD, and OMIM. In this webinar, you will learn how the QIAGEN knowledgebase functions as the cornerstone of our clinical decision support tool (QIAGEN Clinical Insight – Interpret; QCI-I), facilitating rapid variant filtering, interpretation, and reporting across multiple public and propriety databases.