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Progress developing immune-based treatments to treat the highly lethal pancreatic ductal adenocarcinoma (PDA) has lagged behind other cancer types. This may be due, in part, to a fibroinflam...
Immune checkpoint therapy (ICT) is a front-line treatment for lung cancer; however, low mutational burden and ‘non-T cell inflamed’ signatures predict poor responses to ICT in ~5...
Rhabdomyosarcoma (RMS) is a soft tissue cancer commonly arising in muscle and is the most common soft tissue cancer in children. Patients with metastatic RMS have a poor prognosis that has n...
Ovarian cancer is a deadly disease which is usually diagnosed in advanced stages. Our goal is to develop vaccines to prevent relapse. Natural Th17 T cells protect against recurrence followin...
Prostate cancers are considered immunologically ‘cold’ tumors given the very few patients who respond to checkpoint inhibitor therapy (CPI). Recently, enrichment of interferon st...
Chimeric antigen receptor (CAR) T cells have demonstrated significant success in treating relapsed or treatment-refractory hematologic malignancies in the clinic, inducing remissions in 70-9...
Despite the promising results with current approved immunotherapies, all patients do not have the same level of response, and recent efforts have focused on understanding and avoiding immuno...
Learning Objectives: 1. Define “universal CARs” and describe their mechanism of action. 2. Explain current challenges in CAR T cell therapy. 3. Describe potential benefits and ch...
Learning Objectives: 1. Define the impact of PD-L1 expressed on non-tumor, non-hematopoietic cells in T cell-mediated tumor control 2. Reveal the contribution of IFNg signaling in dermal lym...
Date: May 27, 2021 Time: 11:00am PDT, 2:00pm EDT Microbiome studies often suffer from issues that recent technological advances can solve easily. In this seminar, we will walk through planni...
Date: May 27, 2021 Time: 9:00am PDT Since the current SARS-CoV-2 outbreak, there has been an urgent need to define the immune response and understand the relevant immunological mechanisms un...
The increasing spread of variants across the globe raises questions about the effectiveness of existing programs to protect public health. Join Dr. Lauring, a researcher of virus mutations,...
Date: May 26, 2021 Time: 8:00am (PDT) Serious infections can be immediately life threatening: with serious invasive infections a single day can be the difference between life and death for p...
Date: May 25, 2021 Time: 7:00pm PDT Therapeutic drug monitoring (TDM) of Busulfan is essential for management of Bone Marrow Transplant (BMT) patients, by optimizing dose, s...
Date: May 25, 2021 Time: 8:00am (PDT) Reliable expression of recombinant proteins in human, CHO, or insect cells is essential for many aspects of biomedical research and drug development, bu...
Date: May 25, 2021 Time: 8:00am (PST), 11:00am (EST) Therapeutic drug monitoring (TDM) of Busulfan is essential for management of Bone Marrow Transplant (BMT) patients, by optimizing dose, s...
Date: May 20, 2021 Time: 6:00am (PDT), 9:00am (EDT), 2:00pm (BST) In this webinar, Dr Rachel Marrington, Deputy Director, and Finlay MacKenzie, Director, at Birmingham Quality UK NEQAS, will...
Find out what our latest nucleic acid extraction instrument can do for you. How fast can your team get trained on it? Can it process all your sample types? Is it true that it will let you do...
This presentation will describe two microfluidic techniques that my research group has developed for single-cell manipulation and analysis. The first is called Digital microfluidic Isolation...
The effective use of Quality Control (QC) does not stop once QC results are accepted and patient testing begins. The key to reliable patient results and consistent laboratory processes is by...
Date: May 19, 2021 Time: 8:00am PDT Cellular cryo-electron tomography is a high-resolution technique that enables imaging of the molecular machinery of a cell at close-to-native conditions....
Explore the journey of the sample through an automated LC/MS workflow from sample receipt to the reporting of results back into a LIMS. The advantages of automation are discussed, along with...
In 2008, an ALA Survey on Laboratory Automation found that 88% of lab workers believed they would rely on lab automation in the future. Yet it’s 2021, and 72% of scientists now say the...
With the ever-increasing demand for antibody and protein-based therapeutics, a flexible purification platform that can handle low to high sample volumes and expression levels is critical for...
Learning Objectives: 1. Understand the regulatory requirements for clinical sample tracking. 2. Identify the pitfalls of sample tracking during the sample life cycle. 3. Understand how LIMS...
Microfluidic technologies have opened up new possibilities for ultra-low volume, and ultrafast assays, compared to bulk-scale counterparts. We have been focused on developing new tools for d...