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This talk will present the methodology of using the guided ultrasonic waves generated by the rodent to track its physiology, behavior, and psychological state. When behaving in an environmen...
We are developing the three-banded panther worm Hofstenia miamia as a new model system for neuroscience. Hofstenia is a rare, lab-tractable member of a lineage of early-branching marine inve...
The study of psychopathology is changing with the advent and pervasive use of smartphones, wearables, and connected devices together with significant advances in brain imaging. These new ave...
A central goal for neuroscience is to understand how our brains process information in real life, such as faces during natural social interactions. While we have gained important knowledge u...
Speech neuroprostheses have the potential to restore communication to people living with paralysis, but naturalistic speed and expressivity are elusive. Here we use high-density surface reco...
Mental health is a multidimensional challenge, marked by rapid brain changes and essential interpersonal relationships. This complicates the application of traditional statistical methods an...
The ultimate goal of neuroscience is to understand and explain real-world behavior in terms of brain activity, and to use these insights to develop therapeutic approaches for neural disorder...
In recent years, small volume biopsies have been increasingly utilized for diagnosis of tumors in both primary and recurrent settings. Concomitantly, the numbers of ancillary studies for cha...
mRNA‑based products are rapidly growing in the biotherapeutics space. Important considerations need to be made to develop a process for mRNA synthesis that consistently generates high‑yield...
Interoceptive signals dynamically interact with the environment to shape appropriate defensive behaviors. Neurons in the hypothalamus regulate internal states, such as thirst and circadian r...
This presentation explores the pharmacokinetics (PK) and pharmacodynamics (PD) of β-lactam antibiotic dosing, particularly in ICU patients. To optimize PK/PD targets, two strategies are...
Multiplex immunofluorescence is a powerful tool for phenotyping cells from a single tissue slide, while preserving spatial context. The MultiOmyxTM platform, offered as an end to end service...
Learning Objectives: 1. Summarize the benefits and challenges of current preclinical methods in drug discovery and development. 2. Review new alternative methodologies (NAMs) and microphysio...
NAFLD (non-alcoholic fatty liver disease) is a global epidemic that affects 25% of the world’s population, with its epicentre in the West. Twenty percent of NAFLD patients go on to dev...
The study of a single cell, the fundamental unit of our complex bodies, has become an important field in cellular biology, and researchers are using single-cell analysis to shed new light on...
Proliferation biomarkers are proteins that are up-regulated in growing cells. Immunological staining of tumor tissue can provide an indication of the aggressivity of the tumor and provide in...
Globally there has been a constant rise in the population suffering from cardiovascular diseases mostly due to metabolic complications. We have made use of two high throughput omics-based ap...
Central Nervous System (CNS) therapies have significantly progressed in the last decade, propelled by emerging treatment modalities including gene therapies. Neurological indications remain...
Across many cancers, mortality is associated with metastasis and acquired drug resistance, both of which often manifest in recurrent disease. Central to these phenomena is epithelial to mese...
Spatial analysis of protein or gene expression is vital to understanding the distribution, phenotypes, and interactions between cells within tumor microenvironment (TME). Traditionally, mult...
Current cancer research is hindered by the limitations of existing experimental systems, which fall short in demonstrating concordance with human studies. In this way, we aim to develop mode...
Women experience a variety of unique sexual health issues that are often under appreciated by the general public and even by healthcare providers. Compared to other populations, cisgender wo...
Learning Objectives Identify three ways automation improves cryosectioning techniques Demonstrate three essential elements to obtaining reproducible, high-quality sections with cryosectionin...
Over the course of the COVID-19 pandemic, there has been a dramatic increase in the number and type of diagnostic tests for respiratory viruses. These include targeted molecular assays, smal...
Lateral flow assay applications have become increasingly diverse in a post-pandemic world, and the areas of infectious disease and oncology continue to be at the forefront. In both areas, th...
In recognition of World AIDS Day, we invite you to discover the innovative work being done to help end the HIV epidemic in some of the hardest hit areas in India. A diagnosis is the first st...
Pathology Perspective: Discover the critical need for genomic testing in cancer and explore the differences between traditional tissue biopsies and liquid genomic profiling. We'll dive i...