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In the past decade, gene editing has been increasingly emphasized as an essential tool for therapy development. This has led to significant scientific advances in understanding disease mecha...
CRISPR-based diagnostics offer rapid and highly sensitive detection of disease biomarkers. Their ease of use and compatibility with lateral-flow readouts make them suitable for point-of-care...
In this talk, I will introduce two new tools that we developed based on CRISPR-enabled gene regulation in bacteria, and one method based on P1 phagemid-enabled delivery of Cas9 nuclease. Fir...
Smartphone-based optical imaging and sensing devices are among the next-generation biosensors that have shown great potential to transform the field of point-of-care (POC) diagnostics....
Rare diseases pose unique challenges in the medical field, often affecting a small but vulnerable population with limited treatment options. The Rare Disease Challenge (RaDiChal) is a ground...
Programmable genome integration of large, diverse DNA cargo without DNA repair of exposed DNA double-strand breaks remains an unsolved challenge in genome editing. We present programmable ad...
Rather than being famous in gene editing field only, by revealing the collateral cleavage activity of Cas12a, Cas13a, Cas14 effectors, and more, Clustered Regularly Interspaced Short Palindr...
Molecular diagnostics based on clustered regularly interspaced short palindromic repeats (CRISPR) enzyme systems have been the subject of intense research....
Endonuclease Cas12a, as one key part of the CRISPR/Cas biotechnology, possessed a unique dual enzymatic function which has been widely used for various applications1. However, the limits tra...
With the promise of targeted gene editing and CRISPR technologies comes increasing experimental complexity and design challenges. Success in gene editing experiments may depend on many varia...
Gynecologic cancers account for nearly 40% of all cancer incidence and >30% of all cancer mortality in women worldwide. In recent years, there have been significant advancements in the cl...
Gene therapy holds potential for treating neurological diseases by delivering genetic information into specific cell types. However, selective and efficient targeting of cell types remains c...
Neuroscience focuses on the study of the nervous system: a highly complex, dense, and organized network stretching across the whole body of most organisms. Due to this neuroscience can be a...
Description: Join this two-part webinar to learn how capillary electrophoresis (CE) complements sequencing technologies, such as next generation sequencing, that are being used by cancer res...
Clinical laboratories rely on slide staining to clearly analyze components of patient samples and facilitate accurate diagnosis. While automated staining in itself is a great advancement ove...
In the era of advanced biotechnology, automation plays a crucial role in accelerating cancer research. Next-generation sequencing (NGS) technology has revolutionized cancer research, but lab...
Description: Join this two-part webinar to learn when capillary electrophoresis is an ideal choice relative to other various sequencing technologies – such as next generation sequencin...
The CytPix is a flow cytometer that can simultaneously collect fluorescence data and high-resolution brightfield images of individual cells. This allows to better understand the morphology o...
Oxidative stress, a critical factor affecting cell health, has gained prominence in assessing various medical conditions. Given this importance, researchers need a wide range of tools to tho...
Join us for our latest webinar where we will discuss the properties to consider when selecting a hydrophobic filter membrane for specific market applications. Additionally, you will learn ab...
The CytPix is a flow cytometer that can simultaneously collect fluorescence data and high-resolution brightfield images of individual cells. This allows to better understand the morphology o...
This webinar is hosted by Thermo Fisher Scientific in collaboration with the Walter and Eliza Hall Institute of Medical Research (WEHI). The webinar aims to demonstrate the benefits of the E...
Dynamic changes in chromatin drive gene expression programs during cellular development and contribute to pathological changes underlying disease. To date, efforts to characterize chromatin...
DNA comprises molecular information stored in genetic and epigenetic bases, both of which are vital to our understanding of biology in health and disease. The interaction of genetics with th...
Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that closely mimic the complex structure and functionality of human organs. They offer more accurate...