Learn about the latest medical breakthroughs by participating in webinars on topics surrounding disease, prevention and treatment in accordance with the latest research in health and medicine. Updates encompass a biological, psychological and sociological understanding of health.
We recently determined that concurrent inhibition of autophagy, using the lysosomal inhibitor chloroquine (CQ), and of ERK, using a small molecule ERK inhibitor (ERKi), synergistically suppr...
Artificial Intelligence (AI) is a computer program designed to perform operations typical of human intelligence, such as self-learning. AI is taking over different fields in science; we alre...
Prostate cancer (PCa) affects one in nine men and is the most diagnosed solid tumor cancer among men in the United States. The introduction of the prostate-specific antigen (PSA) biomarker b...
Individuals with Lynch syndrome (LS) are prone to develop early-onset mismatch repair deficient (dMMR) colorectal- and endometrial cancers due to germline pathogenic variants (PVs) in one of...
Targeted sequencing has many applications in cancer biomarker research, carrier screening and inherited disorders, drug development, mitochondrial DNA variant detection, human ID and paterni...
The striking conservation between genes involved in cytokinesis and axonal elongation, as well as the morphological similarity between growth cones and migrating cells, raises the question o...
Get to know Luminex’s xMAP® Technology all over again. For 27 years, xMAP Technology has become known as the worldwide leader in bead-based multiplexing. With the new xMAP INTELLIF...
Date: September 21, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Cellular cryo-electron tomography is a high-resolution technique that enables imaging of the molecular machinery of...
α-synuclein (-syn) is a small presynaptic protein linked to the pathogenesis of Parkinson’s disease (PD) and related disorders, collectively called synucleinopathies. Phosphoryl...
Heterotetrameric adaptor protein (AP) complexes play key roles in protein sorting and transport vesicle formation in the endomembrane system of eukaryotic cells. One of these complexes, AP-4...
Within the kidney, the glomerulus is the structure in charge of the renal ultrafiltration. Loss of glomerular function leads to renal damage and could end with irreversible damage. The major...
Intracellular signaling processes are frequently based on direct interactions between proteins and organelles. A fundamental strategy to elucidate the physiological significance of such inte...
In the United States, prostate cancer (PCa) is the second-leading cause of cancer death in men. Multiple observations indicate the link between prostate carcinogenesis, stress of endoplasmi...
Learning Objectives 1) Examine the importance of mechanical forces in cellular activities. 2) Evaluate current strategies for force measurement at the cellular and molecular level. 3) Elucid...
The use of primary human hepatocytes in basic research or other clinical applications (e.g., liver assist devices, ex vivo gene therapy, and hepatocyte transplantation) is limited by a short...
Human Allogeneic Liver-derived Progenitor Cells (HALPC; HepaStemTM) are an advanced therapy medicinal product composed of medicinal signaling cells derived and expanded from healthy human li...
Microphysiological systems (MPS) have proven to be a powerful tool for recreating human tissue- and organ-like functions. However, establishing complex human in vitro ADME models involving c...
Cytomegalovirus (CMV) is one of the most common human herpesviruses, infecting nearly half of the adult population in the US. Vertical transmission can occur during pregnancy, and congenital...
Loop-mediated isothermal amplification (LAMP) uses a stand-displacing DNA polymerase and four to six primers to rapidly amplify DNA at a single temperature. By eliminating temperature cyclin...
Gene Synthesis ensures fast access to nearly any DNA sequence, regardless of its origin or complexity. Its reliability, flexibility and fast turnaround time offer a clear advantage over trad...
Learning Objectives 1. Understand the life cycle of the malaria causing parasite, Plasmodium 2. Understand new approaches to identifying host regulators of infection 3. Describe advantages a...
Since its discovery in late 2019 the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created a global pandemic of coronavirus disease 2019 (COVID-19). As of July of 2022, mo...
Recent outbreaks of Ebola virus (EBOV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have exposed our limited therapeutic options for such diseases and our poor understand...
The COVID-19 pandemic has underlined the need for an efficient collaboration between scientists, policy makers and the general public to tackle the crisis. Infectious disease experts play a...
The lack of preparedness for detecting the highly infectious SARS-CoV-2 pathogen, the pathogen responsible for the COVID-19 disease, has caused enormous harm to public health and the economy...
Altered enteric microorganisms in concert with host genetics shape inflammatory bowel disease (IBD) phenotypes. However, insight is limited to bacteria and fungi. We found that eukaryotic vi...
Getting It Right: Preanalytical Impact on Coagulation Results Using a Case Study Approach According to published literature, up to 65% of errors occur in the preanalytical phase of laborator...
We recently determined that concurrent inhibition of autophagy, using the lysosomal inhibitor chloroquine (CQ), and of ERK, using a small molecule ERK inhibitor (ERKi), synergistically suppr...
