Follow a curation of discoveries and updates in immunology focusing on immune responses to infectious disease, structure and function, and developments in the defense against infection by watching and engaging in these webinars.
SARS-CoV-2 vaccine efficacy testing is now facing increasing challenges in the face of an ongoing pandemic with the emergence of new variants and waning vaccine immunity. Evidence supports t...
Background Protection from SARS-CoV-2 vaccines wanes over time and is compounded by emerging variants including Omicron subvariants. This study evaluated safety and immunogenicity of SARS-Co...
The host antiviral innate immune response protects the host against infection. Like with other viruses, the host recognizes SARS-CoV-2 infection and triggers a series of signaling cascades t...
Vaccines against SARS-CoV-2 have been made in a record time. However, although the vaccines that have been deployed have clearly reduced the percentage of severe infections in countries wher...
The ongoing COVID-19 pandemic has increased awareness about sex-specific differences in immunity and outcomes following respiratory virus infections. Strong evidence of a male bias in acute...
At the end of 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), emerged in China. As of September 2022, SARS-CoV...
Coronavirus Immunotherapeutic Consortium (CoVIC) is an international effort to conduct side-by-side, apples-to-apples comparisons of leading therapeutic antibody candidates against the SARS-...
Date: October 12, 2022, October 13, 2022 Time: 8:30pm (PDT), 11:30pm (EDT), 5:30am (CEST) High dimensional full spectrum flow cytometry holds the promise of addressing long-held questions in...
Date: October 12, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) The microbiome of every food product is incredibly diverse and can include everything from innocuous background flora...
Date: October 11, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) Antimicrobial resistance (AMR) is one of the leading health threats facing humankind. With AMR, microbes can withstand...
Variation in gene expression among cell types, tissues, and organisms is commonly examined by reverse transcription quantitative PCR, or RT-qPCR. In this process, RNA is isolated from sample...
The future of cancer care is contingent on better understanding of molecular, clinical, and outcome data. This can be achieved by leveraging collaborative affiliations and networks locally a...
Single-cell RNA sequencing (scRNA-seq) is an important technology that reveals gene expression differences between different cell types. Yet scRNA-seq data can be challenging to analyze and...
In real-world evidence (RWE), temporal shifts in clinical knowledge and practice need to be adjusted for treatment effect assessment. We use electronic health records (EHR) data to 1) assess...
Breast cancer is the number one cause of cancer in women. Although many risk factors for breast cancer have been identified, only some are modifiable. Since 2004, incidence rates have been r...
Gene regulatory networks are representations of the relationship between transcription factors and their target genes. By modeling gene regulatory networks, it is possible to identify change...
Successful cancer patient advocacy has many components. Patients and survivors are in the best position to tell their stories and advocate for better care and treatment. However, with few su...
Learning Objectives 1. Identify 3 obstacles that inhibit the immune cell response to cancer. 2. List 3 aspects of T cells antitumor function that can be improved with costimulatory signals....
Date: October 05, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) Cancer is a complex disease at the level of both cells and tissues, and uncovering novel treatments requires understan...
Despite the immense promise of cancer immunotherapies, significant challenges have been mounting to overcome treatment resistance and to improve efficacy. Strategies such as the combination...
There are currently several different FDA approved radiopharmaceuticals being used in both large academic and small practice settings to accurately stage and identify local and metastatic pr...
The ultimate promise of tumor immunotherapy is dependent on the generation of effective immunity against cancer, including CD4 and CD8 T cell responses. However, activating T cells in cancer...
The microenvironment of many solid tumors impedes many immunotherapeutic treatments by inhibiting the effector functions of many classes of anti-tumor immune cells, including effector T cell...
Molecular diagnostic tests are currently used for infectious disease testing due to the superior sensitivity and specificity that can be obtained. Due to the success that has been obtained w...
Technological advances in Artificial Intelligence (AI), particularly deep learning, have demonstrated remarkable progress in image-recognition tasks. Methods ranging from convolutional neura...
We recently determined that concurrent inhibition of autophagy, using the lysosomal inhibitor chloroquine (CQ), and of ERK, using a small molecule ERK inhibitor (ERKi), synergistically suppr...
SARS-CoV-2 vaccine efficacy testing is now facing increasing challenges in the face of an ongoing pandemic with the emergence of new variants and waning vaccine immunity. Evidence supports t...
