Follow a curation of discoveries and updates in immunology focusing on immune responses to infectious disease, structure and function, and developments in the defense against infection by watching and engaging in these webinars.
The efficacy of current influenza antiviral drugs is compromised by emerging drug resistance. To address this unmet medical need, we have made progress in developing novel influenza antiviral...
Cancer cells can acquire immune resistance resulting in a loss of immunosurveillance. Tumor cells can upregulate PDL-1 which binds to PD-1. This complex inhibits CD8 Tumor Infiltrating cells...
SARS-CoV-2 vaccine efficacy testing is now facing increasing challenges in the face of an ongoing pandemic with the emergence of new variants and waning vaccine immunity. Evidence supports t...
We use COVID-19 cases, hospitalizations, and mortality data and a deterministic SEIR (susceptible, exposed, infectious and recovered) compartmental framework to model possible trajectories o...
Vaccination and infection are two different paths to immunity. Understanding human immune responses to SARS-CoV-2 RNA vaccines is of interest for a panoply of reasons. mRNA vaccines have dem...
The forecast IHME released on March 26, 2020, was geared to helping hospitals plan for a surge in demand for their resources (e.g., beds, ICUs, ventilators) to fight COVID-19. With many loca...
PerkinElmer is a global leader in the development of instrumentation and probes for small animal non-invasive imaging, including optical and µCT imaging. Through optical imaging, we ha...
The COVID-19 pandemic has taken a dramatic toll worldwide. Its impact possibly has been the most palpable amongst uniquely vulnerable groups of patients, such as patients with a cancer diagn...
The ongoing COVID-19 pandemic has increased awareness about sex-specific differences in immunity and outcomes following respiratory virus infections. Strong evidence of a male bias in acute...
With over 500 million COVID-19 cases and more than 6 million deaths, the COVID-19 pandemic remains a global health threat maintained by the impact of a changing virus. Emerging SARS-CoV-2 va...
Asymptomatic SARS-CoV-2 infection and delayed implementation of diagnostics have led to poorly defined viral prevalence rates. To address this, we analyzed seropositivity in US adults who ha...
Wastewater samples are challenging substrates for nucleic acid extraction, and choice of extraction method will determine the success of downstream analysis. Extraction methods must be able...
Unravelling the expression, distribution and interaction of tumoral markers is crucial for disease diagnostic and treatment. The past decade marks a milestone in the field of tissue analytic...
Dr. John Moore, Professor of Microbiology and Immunology at Weill Cornell Medicine, a Vaccine and Virology researcher, will talk about SARS-CoV-2 vaccines and variants and other topical issu...
Dr. Koenitzer will present an overview of her current research in immune suppression. After a brief introduction to the MILLIPLEX® multiplex immunoassay portfolio, Dr. Koenitzer will dis...
The need for next-generation, broadly protective coronavirus vaccines is underscored by the accelerated pace at which human coronaviruses have been emerging, the evolution of the current pan...
In the US, there are about 75 million individuals less than 18 years of age. COVID-19 has had a major impact on the pediatric population, as there have been more than 13.5 million documented...
Plants recruit soil microbes that provide nutrients, promote growth and protect against pathogens. However, the full potential of microbial communities for supporting plant health and agricul...
Flaviviruses are pathogens of global public health concern. They include dengue virus (DENV), West Nile virus (WNV), and zika virus (ZIKV). There are no approved US Food and Drug Administrat...
As the pandemic continues to evolve, new tools are needed to fight it. The greatest needs revolve around the ability to screen asymptomatic individuals for COVID-19 and to simultaneously tes...
Background: Despite the immunogenicity and safety profile of dendritic cell (DC) vaccines, the importance of vaccine-induced antigen-specific T cell responses is unclear across clinical tria...
Platinum-based chemotherapy has been the cornerstone for treating metastatic urothelial cancer, which compromises the majority of bladder cancer. While urothelial cancer is chemosensitive, p...
Neoantigen based personalized immuno-oncology drugs are a relatively new therapeutic avenue that have shown strong anti-tumor efficacy in the clinic. Neoantigen peptides have been widely rep...
The RNAscope in situ hybridization technology allows high sensitivity, specificity and spatial resolution providing pivotal single-cell gene expression information to gain better insights in...
B cells have recently come into vogue as important contributors to the anti-tumor immune response in cancer patients. Specifically, B cells and the immune structures in which they reside (te...
SARS-CoV-2 testing is now facing increasing challenges in the face of an ongoing pandemic with the emergence of new variants and waning vaccine immunity. Increasing evidence supports the cor...
Learning Objectives 1. Identify 3 obstacles that inhibit the immune cell response to cancer. 2. List 3 aspects of T cells antitumor function that can be improved with costimulatory signals....