Biomedical science combines the fields of biology and medicine that focuses on how cells, organs and systems function in the human body. This is used to enhance knowledge, interventions and technology for healthcare uses.
The zebrafish, Danio rerio, is an ideal model organism to address a broad array of biomedical questions, and is now widely employed to answer questions about aging, behavior, cancer, growth,...
Oftentimes, by the time that laboratory animal facility personnel learn about a facility construction project, the project has been underway for quiet some time without their knowledge but mo...
The rise of zebrafish as a research model has been dramatic. Given the global nature of the work, the rise in shipping zebrafish as a laboratory species has been sharp. Up until this point th...
The environment in which laboratory rodents are kept has an impact on experimental data and breeding performance. The quality of the environment is defined by both the quality of the primary...
The proper surgical techniques represent a key opportunity to improve the welfare of laboratory rodents, while meeting legal and ethical obligations. Use of inappropriate or poor surgical tec...
Regulations and guidelines governing the use of animals in research require minimization of pain and distress. However, pharmacologic treatments to prevent or alleviate pain can interfere wit...
For the purpose of ensuring research integrity, data reproducibility, and animal welfare, institutions that conduct animal research have the responsibility to evaluate vendors that provide la...
The title of this presentation could have been Training within laboratory animal science - where we are and where we should be. While training has been the domain of facility managers for ma...
Abnormal behavior commonly occurs in captive nonhuman primates. It differs from normal behavior in either kind or degree and consists of behaviors such as pacing, self-grasping, and self-inju...
With the growth and expansion of mouse and rat transgenic models in recent years, the demand for surgically altered models mimicking human diseases is growing at an amazing rate. Surgical pro...
Modern biomedical research greatly benefits from sophisticated techniques which can detect even the most subtle alterations between different individuals or groups. This has raised the bar fo...
Training for researchers using animals is a requirement in most European countries. However, somewhat surprisingly, the main actor in providing specific guidelines for such training is a scie...
Rabbits are commonly used in biomedical research for many years due to its ease of use and phylogenetical similarities with humans. They are commonly used in cardiovascular research (atherosc...
Nonhuman primates are commonly used in biomedical research due to its anatomical, behavioral, and genetic similarities with humans. Macaques, especially the Rhesus macaque (Macaca mulatta) ar...
Simplifying Rodent Surgery... Tips for improving technique without incurring unreasonable costs Good science is greatly dependent on minimization of study variables. Surgery has the potential...
The NCI's Therapeutically Applicable Research to Generate Effective Treatments (TARGET) is a comprehensive genomic characterization initiative to determine the molecular changes that drive th...
Personalized medicine is transforming biomedical research and healthcare service delivery. Disease definition, diagnosis, treatment, and prevention are being fundamentally altered by the capa...
Whenever there is cell death, apoptotic cell free DNA fragments appear in the circulation of the host. These fragments, typically 145-160 base pairs in size, represent a minute fraction of to...
Cancer cells have historically been classified by microscopic analysis of blood smears and tissue sections. Current technologies use molecular techniques to categorize and classify tumor cell...
The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision making. Th...
Cancer cells are characterized by major alterations in both cellular metabolism and epigenetic profiles. Current understanding of links between metabolism and chromatin in the context of can...
Malignancies caused by so-called Type I chemical and biological carcinogens provide important opportunities studying early events in cancer development, providing essential information for de...
Since the introduction of second-generation DNS sequencing technologies in 2007, the cost of genome sequencing has been consistently by 33% per quarter, with the $1000 genome arriving in 2012...
Personalized medicine is transforming biomedical research and healthcare service delivery. Disease definition, diagnosis, treatment, and prevention are being fundamentally altered by the capa...
The zebrafish, Danio rerio, is an ideal model organism to address a broad array of biomedical questions, and is now widely employed to answer questions about aging, behavior, cancer, growth,...
Oftentimes, by the time that laboratory animal facility personnel learn about a facility construction project, the project has been underway for quiet some time without their knowledge but mo...
The rise of zebrafish as a research model has been dramatic. Given the global nature of the work, the rise in shipping zebrafish as a laboratory species has been sharp. Up until this point th...
The environment in which laboratory rodents are kept has an impact on experimental data and breeding performance. The quality of the environment is defined by both the quality of the primary...
The proper surgical techniques represent a key opportunity to improve the welfare of laboratory rodents, while meeting legal and ethical obligations. Use of inappropriate or poor surgical tec...
Regulations and guidelines governing the use of animals in research require minimization of pain and distress. However, pharmacologic treatments to prevent or alleviate pain can interfere wit...
For the purpose of ensuring research integrity, data reproducibility, and animal welfare, institutions that conduct animal research have the responsibility to evaluate vendors that provide la...
The title of this presentation could have been Training within laboratory animal science - where we are and where we should be. While training has been the domain of facility managers for ma...
Abnormal behavior commonly occurs in captive nonhuman primates. It differs from normal behavior in either kind or degree and consists of behaviors such as pacing, self-grasping, and self-inju...
With the growth and expansion of mouse and rat transgenic models in recent years, the demand for surgically altered models mimicking human diseases is growing at an amazing rate. Surgical pro...
Modern biomedical research greatly benefits from sophisticated techniques which can detect even the most subtle alterations between different individuals or groups. This has raised the bar fo...
Training for researchers using animals is a requirement in most European countries. However, somewhat surprisingly, the main actor in providing specific guidelines for such training is a scie...
Rabbits are commonly used in biomedical research for many years due to its ease of use and phylogenetical similarities with humans. They are commonly used in cardiovascular research (atherosc...
Nonhuman primates are commonly used in biomedical research due to its anatomical, behavioral, and genetic similarities with humans. Macaques, especially the Rhesus macaque (Macaca mulatta) ar...
Simplifying Rodent Surgery... Tips for improving technique without incurring unreasonable costs Good science is greatly dependent on minimization of study variables. Surgery has the potential...
The NCI's Therapeutically Applicable Research to Generate Effective Treatments (TARGET) is a comprehensive genomic characterization initiative to determine the molecular changes that drive th...
Personalized medicine is transforming biomedical research and healthcare service delivery. Disease definition, diagnosis, treatment, and prevention are being fundamentally altered by the capa...
Whenever there is cell death, apoptotic cell free DNA fragments appear in the circulation of the host. These fragments, typically 145-160 base pairs in size, represent a minute fraction of to...
Cancer cells have historically been classified by microscopic analysis of blood smears and tissue sections. Current technologies use molecular techniques to categorize and classify tumor cell...
The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision making. Th...
Cancer cells are characterized by major alterations in both cellular metabolism and epigenetic profiles. Current understanding of links between metabolism and chromatin in the context of can...
Malignancies caused by so-called Type I chemical and biological carcinogens provide important opportunities studying early events in cancer development, providing essential information for de...
Since the introduction of second-generation DNS sequencing technologies in 2007, the cost of genome sequencing has been consistently by 33% per quarter, with the $1000 genome arriving in 2012...
Personalized medicine is transforming biomedical research and healthcare service delivery. Disease definition, diagnosis, treatment, and prevention are being fundamentally altered by the capa...