Advances in cell and molecular biology have catapulted our understanding of the science of life from the basic understanding of how cells and the components of cells interact within living organisms. Remain up to date on recent discoveries and revelations through these webinars.
Actin cytoskeleton is essential for eukaryotic cells. To exert its countless cellular functions, actin undergoes dynamic remodeling orchestrated by the large number of actin-interacting fact...
Rather than being famous in gene editing field only, by revealing the collateral cleavage activity of Cas12a, Cas13a, Cas14 effectors, and more, Clustered Regularly Interspaced Short Palindr...
Acute T-cell mediated rejection (TCMR) is the most frequent complication after liver transplantation (LT), which can affect up to 50% of LT recipients in the first 5-year post-transplant. Li...
In the United States, prostate cancer (PCa) is the second-leading cause of cancer death in men. Multiple observations indicate the link between prostate carcinogenesis, stress of endoplasmi...
Within the kidney, the glomerulus is the structure in charge of the renal ultrafiltration. Loss of glomerular function leads to renal damage and could end with irreversible damage. The major...
Today, the majority of cell biology operations are carried out manually, even though the core steps are highly reproducible. Staff are expected to conduct repetitive tasks for hours each day...
Molecular diagnostics based on clustered regularly interspaced short palindromic repeats (CRISPR) enzyme systems have been the subject of intense research....
The use of biologic-based therapeutics has revolutionized our ability to treat complex diseases such as cancer- and autoimmune-related disorders. Biologic-based therapeutics are known to gen...
The use of primary human hepatocytes in basic research or other clinical applications (e.g., liver assist devices, ex vivo gene therapy, and hepatocyte transplantation) is limited by a short...
Human Allogeneic Liver-derived Progenitor Cells (HALPC; HepaStemTM) are an advanced therapy medicinal product composed of medicinal signaling cells derived and expanded from healthy human li...
The explosion of interest in extracellular vesicles has largely coincided with the development of tools which allow their rapid and routine characterization, in this presentation we will ide...
Across the entire spectrum of the life sciences sector, from academia and hospitals to pharmaceutical and biotech companies, enormous amounts of resources are invested in the development of...
Cancer is a group of complex genomic diseases. Today still most clinicians, patients ans policymakers think that precision oncology is the sequencing of cancer genomes, which is for many pati...
Gene therapy is defined as the treatment of disease by transfer of genetic material into cells, to prevent, treat and potentially even cure a disease. Gene therapies can work by several mech...
Learning Objectives 1) Examine the importance of mechanical forces in cellular activities. 2) Evaluate current strategies for force measurement at the cellular and molecular level. 3) Elucid...
Measuring the shear rheology for highly temperature sensitive materials is challenging. Material characterization tools are slow compared to industrial processing. Using numerical simulation...
One of the primary limitations in drug discovery and toxicology research is the lack of good model systems between the single cell level and animal or human systems. This is especially true...
Effective process development for viral vector-based medicines is paramount for optimized process efficiency, robustness, scalability, and product quality. Well-designed processes streamline...
mRNA vaccines represent a pivotal innovation in prophylactic healthcare, offering a rapid response to emerging infectious diseases. Leveraging the cellular machinery to produce antigenic pro...
HIV-1 replicates in the body as a large viral population. Along with its high error rate during viral DNA synthesis and its short replication time (24 hours), the virus maintains sequence di...
Microphysiological systems (MPS) have proven to be a powerful tool for recreating human tissue- and organ-like functions. However, establishing complex human in vitro ADME models involving c...
Quantifying critical quality attributes accurately and precisely is an important aspect of regulatory compliance. There is greater demand to optimize processes by integrating advanced analyt...
In the slowly evolving landscape of bioprocess development and manufacturing, digital bioprocess-twins have emerged as potential accelerators. While advanced algorithms are at the heart of t...
The development of cell and gene therapies faces immense pressure in terms of time and cost. Advanced therapy medicinal products (ATMPs) demand stringent quality control measures to ensure s...
Cell and gene therapy is at the forefront of medical innovation, offering transformative potential for treating complex diseases. However, achieving success in these therapies requires metic...
Nanoparticle mRNA Therapeutics has been the focus of intense research driven by the safety profile and several clinical breakthroughs. As of March 2024, there are two mRNA vaccines approved...
Human induced pluripotent stem cells (hiPSCs) are a powerful tool for innovative approaches, such as drug discovery, in vitro disease modelling, or regenerative therapies. However, such proc...
Actin cytoskeleton is essential for eukaryotic cells. To exert its countless cellular functions, actin undergoes dynamic remodeling orchestrated by the large number of actin-interacting fact...
