Advances in cell and molecular biology have catapulted our understanding of the science of life from the basic understanding of how cells and the components of cells interact within living organisms. Remain up to date on recent discoveries and revelations through these webinars.
Analytical ultracentrifugation is an established method during the development of therapeutic proteins and antibodies and contributes supporting information regarding the size, oligomerizati...
Today, the majority of cell biology operations are carried out manually, even though the core steps are highly reproducible. Staff are expected to conduct repetitive tasks for hours each day...
Molecular diagnostics based on clustered regularly interspaced short palindromic repeats (CRISPR) enzyme systems have been the subject of intense research....
Human Allogeneic Liver-derived Progenitor Cells (HALPC; HepaStemTM) are an advanced therapy medicinal product composed of medicinal signaling cells derived and expanded from healthy human li...
The path from research discovery to effective immune cell therapies requires innovative approaches to match the challenges we face. Examining the full richness of biological complexity&mdash...
The use of primary human hepatocytes in basic research or other clinical applications (e.g., liver assist devices, ex vivo gene therapy, and hepatocyte transplantation) is limited by a short...
mRNA vaccines represent a pivotal innovation in prophylactic healthcare, offering a rapid response to emerging infectious diseases. Leveraging the cellular machinery to produce antigenic pro...
Cancer is a group of complex genomic diseases. Today still most clinicians, patients ans policymakers think that precision oncology is the sequencing of cancer genomes, which is for many pati...
In the slowly evolving landscape of bioprocess development and manufacturing, digital bioprocess-twins have emerged as potential accelerators. While advanced algorithms are at the heart of t...
Effective process development for viral vector-based medicines is paramount for optimized process efficiency, robustness, scalability, and product quality. Well-designed processes streamline...
Learning Objectives 1) Examine the importance of mechanical forces in cellular activities. 2) Evaluate current strategies for force measurement at the cellular and molecular level. 3) Elucid...
Measuring the shear rheology for highly temperature sensitive materials is challenging. Material characterization tools are slow compared to industrial processing. Using numerical simulation...
One of the primary limitations in drug discovery and toxicology research is the lack of good model systems between the single cell level and animal or human systems. This is especially true...
Quantifying critical quality attributes accurately and precisely is an important aspect of regulatory compliance. There is greater demand to optimize processes by integrating advanced analyt...
Nanoparticle mRNA Therapeutics has been the focus of intense research driven by the safety profile and several clinical breakthroughs. As of March 2024, there are two mRNA vaccines approved...
HIV-1 replicates in the body as a large viral population. Along with its high error rate during viral DNA synthesis and its short replication time (24 hours), the virus maintains sequence di...
Microphysiological systems (MPS) have proven to be a powerful tool for recreating human tissue- and organ-like functions. However, establishing complex human in vitro ADME models involving c...
Human induced pluripotent stem cells (hiPSCs) are a powerful tool for innovative approaches, such as drug discovery, in vitro disease modelling, or regenerative therapies. However, such proc...
Cultured mammalian cells, particularly Chinese hamster ovary (CHO) cells are widely used in the biotechnology industry for production of a wide range of therapeutics, predominantly monoclona...
As obligate intracellular pathogens, viruses require host-derived nucleotides, amino acids, and lipids, among others, and the bioavailability of these metabolites can restrict or promote vir...
Cell migration is an essential process for many biological phenomena. It plays an important role in disease processes such as wound healing and cancer metastasis. The immune system, which pr...
Gene therapy has revolutionized the field of medicine, and it has the potential to cure a wide variety of genetic disorders. Gene therapy involves the introduction of a functional gene into...
Design of Experiments (DOE) is a powerful and pragmatic tool for optimisation but it’s not the only way. Could there be even more powerful alternatives in the age of machine learning,...
Intracellular signaling processes are frequently based on direct interactions between proteins and organelles. A fundamental strategy to elucidate the physiological significance of such inte...
Cell and gene therapies are on the brink of transforming the pharmaceutical industry, presenting unique challenges such as ensuring the quality and consistent supply of reagents. Reagents pl...
BrainXell offers the most comprehensive portfolio of high-purity iPSC-derived human neurons and glia, sourced from control, edited and disease lines, to advance translational research and dr...
Antibodies are a major component of adaptive immunity against invading pathogens. In this presentation, we will describe an analytical approach to characterize the antigen-specific antibody...
Analytical ultracentrifugation is an established method during the development of therapeutic proteins and antibodies and contributes supporting information regarding the size, oligomerizati...
