Mild traumatic brain injuries (mTBIs) are a prevalent health issue in North America. There is increasing pressure to utilize ecologically valid models of closed-head mTBI in the preclinical...
In this talk, I will discuss the development of interpretable machine learning models to test scientific hypotheses, with a specific focus on spinal motor control. Voluntary movement require...
Explainable AI (XAI) aims at helping you understand and interpret predictions made by AI techniques and tools. Recently, there has been a growing interest in XAI as many users want explanati...
Some of the earliest symptoms of Alzheimer’s disease (AD) are loss of orientation, wandering and misplacing items. One of the first regions vulnerable to AD pathology is the entorhinal...
Selective vulnerability of brain regions and specific neural populations in neurodegeneration remains little understood. We hypothesize that pre-existing physiological differences in neurons...
Black Americans have an increased risk for age-related cognitive decline and Alzheimer's disease (AD) compared to other ethnic and racialized groups. However, risk factors for age-relate...
Date: March 07, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) The ability to synthesize and sequence vast numbers of DNA constructs is a cornerstone of modern high-throughput biologic...
Date: March 07, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) As most labs have moved away from paper record-keeping, electronic lab notebooks (ELNs) have become the de facto solution...
Date: March 01, 2023 Time: 7:00am (PST), 10:00am (EST), 4:00pm (CET) Determining the three-dimensional structure of membrane proteins has historically been a huge challenge for scientists du...
Date: February 28, 2023 Time: 11:00am (PST), 2:00pm (EST), 8:00pm (CET) Traditional methods of infection prevention to detect healthcare-associated outbreaks have remained unchanged for many...
Date: February 28, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Prenatal infections can increase the risk of serious health complications including miscarriage, organ damage, birth...
Date: February 23, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) The RNAscope in situ hybridization (ISH) technology is a powerful method for detecting gene expression with spatial an...
Labroots and the Drug Discovery planning committee are pleased to announce its 6th annual event in the Drug Discovery & Development Virtual Event Series....
Immunogens with native conformation and a high-throughput IgG cloning platform are two of the most important key components for high quality lead antibody molecules discovery. DIMABIO’...
Stago EdVantage Virtual University is an educational platform that demystifies hemostasis testing with on-demand webinars and a virtual exhibit hall that ......
Heparin-Induced Thrombocytopenia (HIT) is a life-threatening complication following heparin exposure. This webinar presentation will discuss the pathogenesis, incidence, clinical...
If you use a pipette on a daily basis, then this webinar is for you. Pipettes are used to prepare samples, blanks, and standards for a range of analytical experiments. This is why the wrong...
Date: February 22, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Circular plasmid DNA has traditionally been used as a stable and efficient vector for gene expression and HDR-mediated...
In general, once a receptor drug target has been validated for the treatment of a particular condition, either a high throughput screen is carried out to identify potential hits, or existing...
Antibody-based therapeutics are helping patients across a wide range of disease areas, from cancer, such as Rituximab treatment of CD20-positive non-Hodgkin's lymphomas, to infectious di...
Non-alcoholic fatty liver disease (NAFLD) is a spectrum of metabolic disorders affecting 25% of our global population. 20% of NAFLD patients go on to develop Non-alcoholic steatohepatitis (N...
Ninety percent of therapeutic agents reaching clinical trial fail to reach entry to market, with safety concerns being a major cause for failures in phase I and II clinical trials. Drug-indu...
The Human Neutrophil Lipocalin (HNL) also called NGAL, Lipocalin 2 etc. is produced by and secreted from epithelial cells and neutrophil granulocytes. In blood HNL exists in several molecula...
Learning Objectives: 1. Describe and discuss some of the unique aspect of in vivo studies. 2. Identify specific study practices to ensure high quality study data and animal welfare. 3. Discu...
G Protein Coupled Receptors (GPCRs) are therapeutic targets for many medications used to treat a variety of disease states. A large number of genetic variants have been identified in the gen...
Many current technologies used in drug discovery and preclinical development programmes typically involve multi-step operations, extensive hands-on time, and lengthy liquid handling processe...
In this project, we optimized a high-throughput fluorescent-based assay to assess transporter activity by measuring uptake of the substrate, ASP+ 4-(4-(dimethylamino)styryl)-N-methylpyridi...
Marine organisms produce a wide variety of primary and secondary metabolites with unique scaffolds that are biologically active. Manzamines are marine-derived polycyclic alkaloids. Approxima...
Advances in tissue-based technologies over the past few years have created opportunities to identify patterns that can be used as biomarkers and prognostic indicators for different disease s...
Novel annotated Patient-Derived tumor Xenografts (PDX) propagated in immunodeficient mice and Organoids (PDO) in Matrigel have become essential models to study inter- and intra-tumor heterog...